Thujone exposure is associated with what toxicity?

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Study for the Gerontological Nursing Certification (GERO-BC) exam. Prepare with flashcards and multiple choice questions, including hints and explanations for every question. Get ready for your exam!

Multiple Choice

Thujone exposure is associated with what toxicity?

Explanation:
Thujone exposure most notably affects the central nervous system. It acts as a GABA-A receptor antagonist, reducing inhibitory signaling in the brain and causing CNS excitation that can lead to tremors, seizures, and perceptual disturbances. This neurotoxic effect is the hallmark of thujone toxicity. While other organ systems can be involved with different toxins, thujone’s characteristic damage is neurotoxicity, not primarily hepatotoxicity, nephrotoxicity, or cardiotoxicity.

Thujone exposure most notably affects the central nervous system. It acts as a GABA-A receptor antagonist, reducing inhibitory signaling in the brain and causing CNS excitation that can lead to tremors, seizures, and perceptual disturbances. This neurotoxic effect is the hallmark of thujone toxicity. While other organ systems can be involved with different toxins, thujone’s characteristic damage is neurotoxicity, not primarily hepatotoxicity, nephrotoxicity, or cardiotoxicity.

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